According to Tottenham Hotspur manager Tim Sherwood, Spurs will be receiving a big boost with four first-team players returning from injury and available for selection this weekend. Gylfi Sigurdsson, Lewis Holtby, and Andros Townsend will all be available to Tim Sherwood, as willsoon-to-depart striker Jermain Defoe. In addition, Sandro and Younes Kaboul have returned to training, but neither will be available to play this weekend. Jan Vertonghen and Paulinho are still out.
Of the returners, I think only Sigurddson and Townsend are likely to feature. Spurs have been hit-or-miss on the wings and one of the two seems likely to be paired with Aaron Lennon in Sherwood's 4-4-2 formation. Holtby's return should be good for Tottenham and many are excited to see him operate in a deeper role. He might be more effective in that role, based purely on workrate, than teammate Christian Eriksen.
Defoe, who the club recently confirmed will be joining Toronto FC in the MLS at the end of February, will likely displace Harry Kane from the bench, and having the experience poacher on the bench to use a super-sub could provide a boost if Spurs find themselves needing a late goal. Hopefully, the players that have returned to training, Kaboul and Sandro, will be available in the coming weeks.